Formulation strategies for poorly soluble molecules - Pharmaceutics and biopharmaceutics considerations
Dr Asma Patel
Quotient Sciences

Speaker’s Bio / Intro:
Dr. Asma Patel is the Vice President of Integrated Development Services at Quotient Sciences, responsible for providing scientific and technical support to Business Development and leading the consequent design of pharmaceutical science programs. Dr. Patel possesses over 20 years of experience in pre-formulation and formulation in academia, industry, and contract manufacturing organisations. Dr. Patel’s expertise covers a wide range of dosage forms, including oral modified release delivery and formulation strategies to improve oral delivery of poorly soluble compounds.

Abstract:
Description: Improving solubility remains one of the greatest barriers to successful drug delivery. Biotech and pharma development teams are constantly under pressure to rapidly advance molecules to the next development milestone and get to market as quickly as possible. However, progress is often constrained by formulation challenges in early-stage drug development, with the prevalence of poorly soluble compounds within the development pipeline, being a prime example.
Join Quotient's Vice President of Integrated Development Services, Dr Asma Patel, as she shares expert insight and case studies on formulation and solubility challenges and discuss the best strategies and technologies for advancing poorly soluble molecules, to deliver success.
Key Learning Objectives:
 Pharmaceutics and biopharmaceutics profiling of NCEs
 The DCS classification system as a foundation for creating a formulation development roadmap
 Formulation strategies for DCS Class IIb compounds
 A review of the formulation technologies available from size-reduction to lipid systems and amorphous forms
 Selecting appropriate biorelevant in vitro characterization methods to inform potential clinical performance
 Choosing the right formulation for preclinical studies and dosage forms for First-in-Human (FIH) studies

An event organised by the Royal Society of Chemistry's Formulation Science & Technology (FST) Interest Group.